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To evaluate the functional relevance of the GLP-1R cholesterol binding sites identified during the cgMD simulations, 12 residues were selected within or at the periphery of these sites and mutated to alanine by site-directed mutagenesis (Figure 2F)

For instance, a Taq1A polymorphism related to striatal dopamine D2 receptor density has been shown to affect the weight loss response to naltrexone/bupropion (43)

Glutathione, Vitamin C

Ann Pediatr Endocrinol Metab (2017) 22(3):14552

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